Environmental Footprint of Peritoneal Dialysis in Europe: A Comparative Life Cycle Assessment Across Four European Centres

Introduction

Peritoneal dialysis (PD) is a home-based renal replacement therapy offering clinical and quality-of-life advantages, but it also poses environmental challenges due to resource use and waste generation. This study compares the environmental impacts of PD across four European centres to identify regional sustainability differences and evaluate the footprint of Continuous Ambulatory (CAPD), Automated (APD), and Incremental (iPD) PD.

Methods

A cradle-to-grave Life Cycle Assessment (LCA) was conducted for one year of PD treatment per patient using OpenLCA software and the EcoInvent database across four clinical centres; Madrid, Warsaw, Utrecht, Modena. Data were collected on material use, energy and water consumption, transportation, and waste disposal. Key indicators included Global Warming Potential (GWP), energy use, water footprint. The environmental performance of each centre and dialysis modality was assessed.

Results

Environmental impacts varied significantly between centres ranging from GWP 3,381 kg CO₂-eq to 1736 kg, reflecting differences in energy mix and efficiency. Energy consumption ranged from 54,710 MJ to 28,894 MJ and water footprint from 6,631 m³ to 854 m³. Across all centres, CAPD and APD had higher environmental burdens than iPD. iPD reduced emissions by up to 50% and had a lower-impact profile.

Conclusions

PD displays substantial environmental impact variability across centres, driven by differences in material consumption, waste management, energy sourcing, and clinical protocols. Cleaner energy profiles, effective waste management, and reduced reliance on single use consumables may lower environmental burdens. These findings underscore the importance of integrating environmental performance into clinical decision-making and health system planning.

Link:  https://doi.org/10.1093/ckj/sfag156

Share this publication

More publications

An In Vitro System for Studying Toxin Transport Across Hemodialysis Membranes

Authors: M. Torrents-Yeste, D. Ramada, O.E.M. ter Beek, F. Pel, J. de Vries, B.H. Lentferink, K.G.F. Gerritsen, D. Stamatialis
Journal: Artificial Organs
Year: 2026

Read more

Toward a closed loop dialysis with urea adsorption by PhenylGlyoxAldehyde (PGA): experiments and modeling

Authors: Diego Caccavo, Joost C. de Vries, Serena De Stefano, Babette H. Lentferink, Jeroen Vollenbroek, Piet Driest, Gaetano Lamberti, Cornelus F. van Nostrum, Karin G.F. Gerritsen
Journal: Chemical Engineering Research and Design
Year: 2026

Read more

Strategies for Removal of Protein-Bound Uremic Toxins in Hemodialysis

Authors: Joost C. de Vries, João G. Brás, Geert M. de Vries, Jeroen Vollenbroek, Fokko P. Wieringa, Joachim Jankowski, Marianne C. Verhaar, Dimitrios Stamatialis, Rosalinde Masereeuw, Karin G.F. Gerritsen
Journal: Toxins
Year: 2026

Read more