Testlab

Our homebase is at the University Medical Center in Utrecht and we offer modular test services providing customizable setups at various scales and environments (small to large scale, and in silico to in vitro and in vivo). Our testlab aims at facilitating preclinical studies for dialysis innovations in a streamlined pipeline to get these innovations from bench to bedside. We offer dialysis simulation experiments on multiple scales (small, medium, large) starting at volumes less than 50 mL and going up to real dialysis scale with volumes of 180L. We can measure all relevant uremic toxins (e.g. urea, creatinine, in-line and real-time protein bound uremic toxins, etc) and perform in-vitro experiments with aqueous solutions, whole blood and (uremic) plasma. For in-vivo experiments we have validated uremic animal models (goat, pig, and soon rat). Furthermore, we offer precise control over flow, pressure and temperature. Finally, our medical technology and clinical physics department is ISO13485 certified ensuring high quality support for development of medical devices for future clinical trials. Additionally, we offer a rapid prototyping facility to develop custom components that are required for testing.  

The realization of the testlab has been enabled by the NXTGEN Hightech growth fund.